Sinai Health scientists are learning how to guide chemotherapy drugs to target cancer cells and leave normal cells unscathed, minimizing the toxic impact on patients’ healthy tissues and reducing the side-effects they experience.

They are exploring how to harness the immune system to identify and attack cancers that would normally be invisible to it. And they are inventing ways to foresee how a tumour will behave, to guide treatment strategies and spare patients from unnecessary and toxic drug therapies.

The Lunenfeld-Tanenbaum Research Institute is ranked number one in the world for high-impact diabetes research publications, and our scientists are among the most highly cited compared to any other diabetes research program.

LTRI research has led to a number of new treatments for people living with diabetes. For example, breakthroughs include the development of two new classes of drugs that help blood sugar management by improving gut hormone action, which have become transformative in diabetes care today.

Sinai Health’s Lunenfeld-Tanenbaum Research Institute (LTRI) is an international neuroscience research leader. Our discoveries are forming the basis of new biomarkers, drugs and interventions that will lead to a future where doctors can detect, slow, prevent and reverse brain diseases and damage that can happen at any age.

Our research impacts people with: Alzheimer’s disease, dementia and neurodegeneration; disability resulting from stroke damage; traumatic injury to the brain or spinal cord; multiple sclerosis and Parkinson’s disease and other degenerative neuromuscular disorders; autism and other congenital neurodevelopment diseases; depression, anxiety and mood disorders; and psychotic disorders such as schizophrenia.

Sinai Health is home to one of the largest and most advanced women’s and infants’ program in the country. Research supporting the program will lead to better in vitro fertilization outcomes, provide faster diagnosis pain relief for women experiencing pelvic pain, and enhance the care of pregnant women with heart disease, cancer, kidney disease and many other challenging conditions.

For fragile premature babies, we’ve invented and tested a new model of care that includes parents as members of the health-care team and fully prepares them to look after their fragile babies at home. Our approach is proven to help preemies gain weight faster.